Color coding is also applied in Franklin to distinguish between different regulatory region sources, particularly in the context of enhancers and promoters. This feature enables users to quickly identify the origin of regulatory annotations and assess their experimental basis or computational confidence.
The following colors represent the source of the regulatory data:
Turquoise or Gray | Ensembl: |
Blue | Vista Enhancer Browser |
Yellow | Other Sources: Additional regulatory annotations from various research databases or internal datasets not covered by Ensembl or Vista. |
These color cues appear within the genome browser and variant interface when relevant, particularly in the Regulatory track. Enhancer and promoter elements can influence gene expression, and identifying their source supports the interpretation of variants in non-coding regions.
See an example of Color Coding in Variants > Regulatory:
See an example of Color Coding in Variant Interpretation Hub > Somatic Clinical Evidence: