Franklin automatically stores all your variant classifications from past cases into your organization's Knowledge Base, which is shared with the rest of your team members. In addition, you can now import your classified CNV historical repository very easily, providing a unified database of your previously curated data.
In order to import your previously classified list of variants, head over to your KNOWLEDGE BASE, and then to the Variants tab. There, you can find all the curated variants that you or your teammates have classified using Franklin. To learn more about building your organizational Knowledge Base, check out this article.
To import your variant repository from an external software, such as ChAS or excel, into Franklin, click the + Add variants blue button on the right. A pop-up will show and you can either drag and drop your files or browse on your computer to select them.
Please note that the files need to have a specific tabular format. The mandatory columns include the Variant Change (deletion/loss or duplication/gain), the Chromosome, and the Start and End points. The optional fields are Classification Date, Classification, Associated Conditions, Probands, Interpretation Text, and Associated Publications. You can download the template on TSV or XLS.
Finally, you should click on the Submit button, and you're done! You've imported your historical repository of classified variants into Franklin, integrating all your clinical data in one unified database.
Still have questions? Reach out to our Support Team, they'll be happy to help!