With great features come exceptional capabilities.
Franklin Premium is designed to empower labs with a complete, end-to-end solution, streamlining everything from raw data processing to customized report generation. With robust, scalable features tailored to modern lab environments, Franklin Premium supports your lab’s growth and adaptation to new challenges. Our suite of advanced capabilities ensures seamless integration, data security, and flexibility, helping labs optimize workflows, enhance accuracy, and meet compliance standards.
Explore the premium features below to discover how Franklin can be a pivotal resource in supporting your lab’s evolving needs.
1. Seamless End-to-End Pipeline Automation
Franklin enables seamless automation across your entire bioinformatic pipeline, from raw data to final reports. Supporting both secondary and tertiary analyses with FASTQ, BAM, VCF, and bulk uploads, Franklin simplifies data handling to provide thorough, actionable evidence and accurate results. This comprehensive automation empowers your lab to efficiently process large volumes of in-house datasets and workflows, focusing on generating insights while maintaining precision and control at every stage.
2. Unlimited Workflow Compatibility
As a premium subscriber, you gain unlimited access to over 500 validated workflows, numerous assays, and more than 40 customizable QC metrics. This extensive compatibility ensures Franklin integrates seamlessly with a wide range of sequencers and kits, meeting your lab’s needs both now and into the future.
3. Customizable Report Generation
Beyond standard reporting.
Franklin’s customizable reports can be fully adapted to your lab’s specific requirements, incorporating all necessary information to meet lab protocols and comply with governmental or national regulations. Reports can be exported in Word, PDF, or JSON formats, allowing seamless integration with existing LIMS or EMR systems and ensuring flexibility in data documentation. Using our role based Permissions mechanism, premium users can assign designated team members to review, classify, and sign the final report, enhancing accountability and compliance
4. Advanced CNV Detection Algorithm:
Franklin’s premium subscribers enjoy exclusive access to ‘Rainbow,’ Franklin’s proprietary CNV variant caller explicitly designed for precise CNV detection. ‘Rainbow’ leverages machine learning and Franklin’s AI engine to deliver high-quality results tailored to your lab’s protocols. As part of your subscription, the Franklin team will train your CNV model using your lab’s data, creating a custom model that aligns precisely with your standards for highly accurate and reliable results.
5. Proprietary Secondary Analysis Platform
Franklin’s secondary analysis platform integrates multiple variant callers to detect SNPs, indels, CNVs, and other variant types with exceptional precision.
In-house tools such as Mouflon (mitochondrial deletions), Apricot (long indels), and Rainbow (CNV detection) are specifically designed to address common challenges in variant calling, ensuring high accuracy and reduced false positives.
Data integration: Identical variants detected by multiple callers are merged into a unified variant, while distinct calls remain separate.
Confidence scoring: Each variant is assigned a score based on various parameters, ensuring reliability in downstream analyses.
Flexibility: Export FASTQs, BAMs, and VCFs directly from Franklin’s UI or automate the process via API.
These features enable labs to handle complex datasets with confidence, supporting their protocols and research goals.
6. Direct API Integration
Automate data handling and streamline analysis workflows with a direct API connection, designed to optimize data management and reduce turnaround times. Our API supports automated case creation and assignment via sample sheets, integration with data sources, and efficient bulk upload capabilities.
7. LIMS and EMR System Integration
Franklin offers direct integration with LIMS and EMR systems to ensure smooth data flow and streamlined workflow management. Clinical input files can be populated directly into the Franklin system, and customizable reports can be exported seamlessly into your internal system, enhancing efficiency and consistency in data handling.
8. Integrated Knowledge Base
Bootstrap your Franklin's knowledge base with historical data.
With Franklin, your curated and classified data is preserved as a valuable resource in Franklin’s Knowledge Base. Historical classifications provide a baseline for future case investigations, and users have the flexibility to share data internally, within a consortium, or with the broader community. Premium users can also seamlessly import historical data from previously owned systems, ensuring no data is lost and enhancing classification and curation capabilities from day one.
9. Private and Secure Data Storage Access
Premium subscribers receive complimentary access to a private Amazon S3 bucket, providing a unified, secure storage solution for clinical data. Access your data from anywhere with full compliance with HIPAA and GDPR regulations, ensuring the highest standards of privacy.
10. Biomarker Support
Franklin supports a wide range of biomarkers, including HRD, TMB, and MSI, enabling comprehensive clinical and research analyses.
