Here's what's new on Franklin (2022.1)

January 2022 release updates

Updated over a week ago

Franklin continues to grow and improve with every version. Here are some interesting freshly released features, as well as some general usability updates to make sure our users get the most out of the Franklin Community:

#1: New! Low-Pass sequencing workflow

As part of Franklin's commitment to supporting all workflows in the genetic field, we're very excited to announce that we now fully support NGS whole genome low pass sequencing.

In line with this new solution, we have also been working on improving Franklin's ability to call CNVs on whole genome sequencing. Franklin now supports even relatively low mosaics.


#2: Knowledge Base gene panels

We've developed a new way to create and manage your organization's gene panels! In order to improve user experience, we created a better user interface for panel management.
Panels are now located under the Knowledge Base tab - the one place where all your organization's clinical knowledge is centralized. You can easily create a panel and add genes to it.

Franklin Knowledge Base gene panels

#3: The Mexican database

As always, we’re working to encourage collaboration within the genetics community and generate insights to improve precision medicine worldwide. That’s why Franklin partnered up with two renowned healthcare institutions in Mexico to release the first genomic database to represent exclusively the Mexican population.
This first version of the Mexican database comprises 1.2 million variants from 480 samples provided by INMEGEN and the Institute of Ophthalmology Conde de Valenciana, and can be found on Franklin in the Population Frequencies tool, located on the Variant Assessment application.

Franklin Mexican database in Population Frequencies

Additional improvements

In somatic analysis:

  • Franklin's clinical team added new therapeutic evidence for tumor analysis cases

  • The Report Wizard is now updated

  • Improved OCA workflow is now available

  • Some minor improvements were made in the classification process

In our community features:

  • You now have the option to filter cases in the Franklin Community Frequency widget according to your country

  • Bug fixes on the gene curation process

In general:

  • Sex chromosome variant interpretation is now improved


We hope you find these updates useful! We encourage you to give them a try and share your thoughts. We appreciate your feedback.

If you’re interested in learning more about these new features, or want to explore analyzing FASTQ files and exporting custom reports with Franklin+, feel free to schedule a call with us!

- The Franklin Team


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