Introduction
Franklin allows users to generate and associate virtual panels with analysis in order to easily and quickly filter results based on predefined lists of genes or regions.
Navigation
To generate a virtual panel, or review the existing panels added to the organization - navigate to the "Knowledge Base" section from the top menu, and then click on the "Panels" tab.
Create a new Panel
Choose the "Add" button, and select the "Create Panel" item from the menu
Select a meaningful name, and provide additional information on the panel such as the type of samples, clinical domain and phenotypes that are associated with it
Add genes to your panel
Option one: Import Gene List from a TSV file
The recommended way to create a new panel is by importing a list of genes from a TSV file.
For documentation on how to add panels from a file, please follow here
Franklin would provide you with downloadable examples for curated gene list structure and a simple gene name list.
2. Option two: Adding a Gene to the panel
Click on the "Add" to choose the "Select genes" option, to add genes from the user interface, tip: you can add multiple genes by comma separated values (e.g TP53,EGFR)
Your gene panel will be added to the "Organizational Knowledge Base" and you can review it or edit it from there.
Using the panel
When the panel is ready you can use it to filter your case results by adding it to the panels' list in the panels' filter
Still have questions? Reach out to our Support Team, they'll be happy to help!