Franklin employs an advanced classification tool based on ACMG guidelines, to automatically identify and prioritize pathogenic variants. The classification tool is powered by artificial intelligence technology and supports inside organization workflows of classification using a hierarchy scheme automatically ranking variants by using user-supplied phenotype and genotype data in conjunction and providing users with tools to choose or accept suggested classification.
The 5 suggested classifications are based according to ACMG guidelines:
Pathogenic
Likely Pathogenic
Uncertain level-Possibly pathogenic,Uncertain significance,Possibly benign
Likely Benign
Benign
To learn more about Franklin ACMG automated classification visit these articles-
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