Franklin is a cutting-edge platform designed to cater to the diverse needs of professionals in the genetic field, offering a user-friendly and intuitive experience. With both Freemium and Premium options, Franklin provides a range of tools and unique insights, fostering collaboration and improvement across fields and countries. Unlike a 'black box,' Franklin offers transparent access to detailed information from trusted public sources and our exclusive community insights, ensuring the trust and confidence you need in your interpretation work.
The Franklin platform revolves around three key applications: Search, Knowledge Base, and My Cases.
Search
You can question either a single nucleotide variant (SNV), copy number variant (CNV), or regions of homozygosity (ROH), either germline or somatic variant, and select either HG19 or HG38 as the reference genome.
Once you enter the variant name into the search box, simply indicate any relevant clinical evidence and click the 'Search' button. This will navigate you to Franklin's 'Variant Interpretation Hub.'For more detailed insights into Franklin's 'Variant Interpretation Hub,' click here.
Knowledge Base
Franklin's Knowledge Base functions as a centralized repository designed to support the organization and management of genetic data. Users can configure customized gene panels, access curated gene databases, and review or manage classified variants. The Knowledge Base provides structured access to essential data to support consistent and informed interpretation workflows. Franklin's Knowledge Base serves as an organizational repository, housing a wealth of your essential genetic data. This resource allows you to configure personalized panels, access curated gene databases, and easily review and manage classified variants.
To navigate the Knowledge Base we invite you to read our informative article.
My Cases
The 'My Cases' application in Franklin serves as a centralized repository for all your organization's cases. It offers a seamless platform to initiate case analyses, review past cases, manage ongoing cases with your teammates, and track and update analysis statuses.
Within the 'My Cases' screen, each case is represented by a tile, featuring the case name, workflow icon, and dedicated assay information. Furthermore, you have the flexibility to add labels, assign cases to other team members, and perform various other actions to streamline case management.
To explore the full range of offerings provided by the 'My Cases' application, including uploading a new case and accessing the 'Germline Dashboard,' click here.