Franklin is a cutting-edge platform designed to cater to the diverse needs of professionals in the genetic field, offering a user-friendly and intuitive experience. With both Freemium and Premium options, Franklin provides a range of tools and unique insights, fostering collaboration and improvement across fields and countries. Unlike a 'black box,' Franklin offers transparent access to detailed information from trusted public sources and our exclusive community insights, ensuring the trust and confidence you need in your interpretation work.

The Franklin platform revolves around three key applications: Search, Knowledge Base, and My Cases.

The Search application serves as a versatile platform for in-depth interrogation of specific variants. You can question either a single nucleotide variant (SNV), copy number variant (CNV), or regions of homozygosity (ROH), either germline or somatic variant, and select either HG19 or HG38 as the reference genome.

Once you enter the variant name into the search box, simply indicate any relevant clinical evidence and click the 'Search' button. This will navigate you to Franklin's powerful 'Variant Interpretation Hub,' a dedicated space designed for comprehensive interrogation. Within the hub, you'll find multiple tabs and a wealth of information to explore further. For more detailed insights into Franklin's 'Variant Interpretation Hub,' click here.

Franklin's Knowledge Base serves as a robust and centralized organizational repository, housing a wealth of your essential genetic data. This invaluable resource allows you to configure personalized panels, access curated gene databases, and easily review and manage classified variants. With Franklin's Knowledge Base, you have the power to organize and streamline your genetic information, empowering you to make informed decisions and accelerate your research and analysis workflows.

To navigate the Knowledge Base more efficiently and take full advantage of its rich features, we invite you to read our informative article.

The 'My Cases' application in Franklin serves as a centralized repository for all your organization's cases. It offers a seamless platform to initiate case analyses, review past cases, manage ongoing cases with your teammates, and track and update analysis statuses. This powerful tool empowers you to efficiently organize and access your case data, enabling seamless collaboration and enhanced productivity.

Within the 'My Cases' screen, each case is represented by a tile, featuring the case name, workflow icon, and dedicated assay information. Furthermore, you have the flexibility to add labels, assign cases to other team members, and perform various other actions to streamline case management.

To explore the full range of offerings provided by the 'My Cases' application, including uploading a new case and accessing the 'Germline Dashboard,' click here