We are happy to introduce several enhancements and new features in our latest update:
Free Accounts: In-App Chat Support No Longer Available
Starting from this version, the in-app chat support interface will no longer be available for free accounts. Free account users can contact us at [email protected] for sign-in/password assistance and critical blocking issues (excluding file upload issues). For all other issues, free account users can search for solutions and information directly in Franklin Help Center.
Import Somatic and Oncogenic SNPs to Knowledge Base
The Knowledge Base now supports importing SNPs with somatic or oncogenic interpretations. The SNP template is available for download as a XLSX or TSV file as before, but now supports somatic and oncogenic interpretations in addition to germline interpretations.
Importantly, the updated template includes the new mandatory column “Classification System”, which requires filling a single value per row - germline, somatic, or oncogenic - for creating a clear distinction between these classifications. Notably, in a somatic or an oncogenic variant row, only a single condition can be filled for that row.
Moreover, it is possible to submit sub-tiered classifications, e.g. “Tier 1A”, if this option is configured for your organization generally.
For more information on importing variants and the updated template, please visit the following Franklin Help Center article.
Tumor Cases: Support for Gene Panels in Sample Sheet
In tumor (somatic) cases, sample sheets now support the use of soft panels and hard panels, including single-gene hard panels. Similar to the germline sample sheet, panels are added from the optional columns “soft panels”, “hard panels”, and “hard panels single genes”. The new panel columns are available for both S3 and BaseSpace uploads. For more information on panels in the somatic sample sheet, please visit the following Franklin Help Center article.