Key New features:
New Variant Table View
We’re delighted to introduce a new feature in Franklin: the Variant Table View. This addition is a direct response to the valuable feedback we’ve received from our users, aiming to offer a more versatile way to interact with variant data.
Key Features:
Table Format: The Variant Table View presents your variant list in an alternative format alongside the existing variant tiles.
Same Data and Actions: Enjoy consistency and functionality as all data and actions available in the current variant tiles are replicated in the table view.
Customization: Tailor your experience by choosing which fields to display in the table and their order. Your preferences will be saved for future sessions, ensuring a personalized workflow.
To access the Variant Table View:
Navigate to the top right corner of the page.
Find the table icon located below the ‘Manage Filters’ button.
Click on the table icon to switch to the table view.
Please note that the Variant Table View is currently available exclusively for SNP germline Variants..
If you have any questions or feedback regarding the Variant Table View, please don’t hesitate to reach out to us.
gnomAD v4.0
gnomAD population frequencies for hg38 single-nucleotide variants are now updated to v4.0 release. This release includes a larger and more diverse set of individuals, together with improved QC metrics for filtering.
For SNVs aligned to build hg19 of the human reference genome, currently gnomAD v2 will continue to be used.
Note that v4 release does not contain updated mitochondrial frequencies over v3 version.
Discovery Analyses page
We added an easier workflow to analyze your Discovery data and enhance cohort studies from a new “Discovery Analyses” page.
After applying filters in the “Germline - All” Discovery analysis and saving specific cohorts, you can now create additional Discovery analyses from 1 or 2 (case-control) cohorts.
The new Discovery Analyses page will display all the Discovery Analyses, alongside the “Germline - All” Discovery analysis, to gain better access and view of your repository genomic data.
New variant tile design
As part of our commitment to improving your user experience, we have made noteworthy enhancements to our Variant Tile Design in the Franklin software. This new design not only revamps the look and feel of the tiles but also incorporates new and improved data points to aid your variant initial assessment process.To read more, check out this article.