Franklin ACMG Automated Classification
Read more about Franklin’s ACMG Classification engine
By Assaf and 1 other2 authors7 articles
- Gene missense sensitivity rules - PP2, BP1
- Prediction tools PP3, BP4
- Frequency rules - PM2, BS1, BS2, BA1
- Reported variants rules - PP5, BP6, PS1, PM5The following rules PP5, BP6, PS1, PM5 rules are based on evidence coming from known classified variants
- Loss of function rule - PVS1Here you can find more details about Franklin's implementation of the ACMG PVS1 rule used for SNP variants classification
- Hotspot rule - PM1Here you can find more details about Franklin's implementation of the ACMG PM1 rule used for SNP variants classification
- Franklin ACMG/ClinGen CNV classification